| Spaceport Trench Tower Key | Unlocks a door to the Trench Towers in Spaceport | Uncommon |  100 | 0.25 kg | Key |
| Spaceport Warehouse Key | Unlocks a door in the Shipping Warehouse in Spaceport | Uncommon | 100 | 0.25 kg | Key |
| Speaker Component | Used in crafting. | Rare | 500 | 0.3 kg | Topside Material |
| Spectrometer | Can be recycled into crafting materials | Rare | 3000 | 1.5 kg | Recyclable |
| Spectrum Analyzer | Can be recycled into crafting materials | Epic | 3500 | 1.5 kg | Recyclable |
| Spotter Relay | Can be recycled into crafting materials | Uncommon | 1000 | 1 kg | Recyclable |
| Spring Cushion | Can be recycled into crafting materials. | Rare | 2000 | 2 kg | Recyclable |
| Stable Stock I | Slightly improves dispersion & recoil recovery time. Compatible with: Rattler, Ferro, Arpeggio, Bettina, Kettle. | Common | 640 | 0.25 kg | Modification |
| Stable Stock II | Moderately improves dispersion & recoil recovery time. | Uncommon | 2000 | 0.5 kg | Modification |
| Stable Stock II Blueprint | Lets you craft a Stable Stock II | Legendary | 5000 | - | Blueprint |
| Stable Stock III | Significantly improves dispersion & recoil recovery time. | Rare | 5000 | 0.75 kg | Modification |
| Stable Stock III Blueprint | Lets you craft a Stable Stock III | Legendary | 5000 | - | Blueprint |
| Stack of Movie Tapes | A stack of movie tapes, sure to please even the most pedantic of cinephines. | Common | 0 | 0.5 kg | Quest Item |
| Statuette | A small decorative statuette. | Rare | 3000 | 0.3 kg | Trinket |
| Steel Spring | A tightly wound coil of metal. Used to craft a wide range of items. Can be recycled into scrap metal. | Uncommon | 300 | 0.25 kg | Topside Material |
| Stella Montis Archives Key | Unlocks a door in the Archives in Stella Montis | Epic | 100 | 0.25 kg | Key |
| Stella Montis Assembly Admin Key | Unlocks a door in Assembly in Stella Montis | Uncommon | 100 | 0.25 kg | Key |
| Stella Montis Medical Storage Key | Unlocks a door in Medical Research in Stella Montis | Uncommon | 100 | 0.25 kg | Key |
| Stella Montis Security Checkpoint Key | Unlocks a door in the Security Checkpoint in Stella Montis | Rare | 100 | 0.25 kg | Key |
| Sterilized Bandage | A medical item that gradually restores a large amount health over time. | Rare | 2000 | 0.2 kg | Quick Use |
| Stitcher I | Full automatic SMG. Deals good damage, but has quite a low fire-rate and can be hard to control. | Common | 800 | 5 kg | Weapon |
| Stitcher II | Full automatic SMG. Deals good damage, but has quite a low fire-rate and can be hard to control. | Common | 2000 | 5 kg | Weapon |
| Stitcher III | Full automatic SMG. Deals good damage, but has quite a low fire-rate and can be hard to control. | Common | 3000 | 5 kg | Weapon |
| Stitcher IV | Full automatic SMG. Deals good damage, but has quite a low fire-rate and can be hard to control. | Common | 5000 | 5 kg | Weapon |
| Succulent (Backpack Charm) | Complete the quest The Root Of The Matter to get this charm. | - | 0 | - | Misc |
| Surge Coil | A deployable device that periodically electrifies the area around itself and briefly stuns anything caught within it. | Rare | 0 | - | Deployable |
| Surge Coil Blueprint | Lets you craft a Surge Coil. | Legendary | 5000 | - | Blueprint |
| Surge Shield Recharger | A handkeld kit that recharges a shield | Rare | 1200 | 0.2 kg | Quick Use |
| Surveyor Vault | Can be recycled into crafting materials. | Rare | 1000 | 1 kg | Recyclable |
| Synthesized Fuel | Used to craft utility items and explosives. Can be recycled into chemicals. | Rare | 700 | 0.5 kg | Topside Material |
| Syringe | A sterile syringe for medical use. Used to craft medical supplies. Can be recycled into plastic. | Rare | 500 | 0.3 kg | Topside Material |
| Tactical Mk. 1 | Basic tactical augment. More Quick Use slots for more tactical choice, but limited survivability and slightly lower looting potential. | Uncommon | 640 | 2 kg | Augment |
| Tactical Mk. 2 | Adds more backpack space and an extra utility item slot. | Rare | 2000 | 2 kg | Augment |
| Tactical Mk.3 (Defensive) | A defence-focused augment for keeping shields topped up. | Epic | 5000 | 5 kg | Augment |
| Tactical MK.3 (Defensive) Blueprint | a defense-focused augment for keeping Shields topped up | Legendary | 5000 | - | Blueprint |
| Tactical Mk. 3 (Healing) | A healing-focused augment which adds extra slots for healing items. | Epic | 5000 | 4 kg | Augment |
| Tactical MK.3 (Healing) Blueprint | A healing-focused augment which adds extra slots for healing items. | Legendary | 5000 | - | Blueprint |
| Tactical MK. 3 (Revival) | A tactical augment focused on utility over defense and looting. | Epic | 5000 | 3 kg | Augment |
| Tactical Mk. 3 (Revival) Blueprint | Lets you craft Tactical MK. 3 (Revival) Blueprint. | Legendary | 5000 | - | Blueprint |
| Tagging Grenade | A grenade that detonates after a delay, tagging Raiders and ARC enemies in an area, allowing you to briefly track their location. | Rare | 1000 | 0.4 kg | Quick Use |
