 Infection Res Plasm | Consumables · Medical | Food Station | Stack 100 |
 Infiltrator LEM | LEMs · Movement | Found in the world | Increases Fog of War area uncovered by the player by 25% |
 Interior Power Generator | Buildings · Power | | +100 MW |
 Intermediate Building Material | Materials · Building Materials | Basic Item Printer or Mega Press | Stack 1,000 |
 Ion Bomb | Components · Late game | Facturer | Stack 100 |
| Ion Bomb - Blueprint | Blueprints · Not required | | |
 Ion Injector | Components · Mid game | Compounder or Constructorizer v.2 | Stack 100 |
 Ion Injector - Blueprint | Blueprints · Not required | | |
 Ion Stabilizer | Components · Late game | Mega Press | Stack 100 |
 Ion Stabilizer - Blueprint | Blueprints · Not required | | |
 Ion Thrusters | Components · Late game | Constructorizer | Stack 100 |
 Irrigator LEM | LEMs · Survival | Found in the world | Reduces natural Hydration loss by 20% |
 Key Card | Key Items · Keycards | | |
 L.E.M. Station | Buildings · Stations & Terminals | Future Health Solutions | |
 Ladder | Buildings · Platforms & Walkways | Griffith Blue Corporation | |
 Large Habitat | Buildings · Habitat & Storage | Selenian Corporation | |
 Large Personal Storage | Buildings · Habitat & Storage | Clever Robotics | |
 Laser Drill | Buildings · Extraction | Selenian Corporation | 250 MW · 1 recipes |
 Laser Emitter | Components · Mid game | Assembler or Constructorizer v.2 | Stack 100 |
 Laser Emitter - Blueprint | Blueprints · Not required | | |
 Launcher Ammo Not in the game yet | Weaponry · Ammo | | Stack 100 |
| LEM Station | Buildings · Stations & Terminals | Future Health Solutions | |
 Lens | Components · Mid game | Compounder or Compounder T2 | Stack 100 |
 Lens - Blueprint | Blueprints · Not required | | |
 Lesser Aimer LEM | LEMs · Combat | Found in the world | Increases Aim Speed by 20% |
 Lesser Airjumper LEM | LEMs · Movement | Found in the world | Reduces Double Jump cost by 20% |
| Lesser Companion LEM | LEMs · Combat | Found in the world | Reduces Damage Dealt and Received from Friendly Fire by 20% |
 Lesser Deatheater LEM | LEMs · Survival | Found in the world | Reduces Resource-, Combat-, and Consumable-type item loss on death by 5% |
| Lesser Detoxifier LEM | LEMs · Survival | Found in the world | Reduces Toxicity intake by 20% |
| Lesser Dietician LEM | LEMs · Survival | Found in the world | Reduces natural Calorie loss by 10% |
| Lesser Dodger LEM | LEMs · Movement | Found in the world | Reduces Dodge cost by 25% |
| Lesser Endurancegiver LEM | LEMs · Movement | Found in the world | Increases Max Stamina by 30 |
| Lesser Fallguy LEM | LEMs · Movement | Found in the world | Reduces Fall Damage by 20% |
| Lesser Fixer LEM | LEMs · Combat | Found in the world | Reduces Tool cooldown by 12% |
| Lesser Glutton LEM | LEMs · Survival | Found in the world | Increases all consumable stats by 20% |
| Lesser Immuner LEM | LEMs · Combat | Found in the world | Reduces Infection build-up rate by 20% |
| Lesser Infiltrator LEM | LEMs · Movement | Found in the world | Increases Fog of War area uncovered by the player by 15% |
| Lesser Irrigator LEM | LEMs · Survival | Found in the world | Reduces natural Hydration loss by 12% |
| Lesser Lifegiver LEM | LEMs · Survival | Found in the world | Increases Max Health by 15 |
| Lesser Lifegiver LEM | LEMs · Combat | Found in the world | Increase Max Health by 12 |
| Lesser Liner LEM | LEMs · Movement | Found in the world | Increases Zipline travel speed by 20% |
| Lesser Miner LEM | LEMs · Survival | Found in the world | Increases Harvester mining damage by 8% |
| Lesser Reloader LEM | LEMs · Combat | Found in the world | Increases reload speed by 14% |
| Lesser Reprinter LEM | LEMs · Survival | Found in the world | Increases Health, Hydration, and Calorie levels after respawn by 100% |
| Lesser Resister LEM | LEMs · Survival | Found in the world | Reduces Heat, Corrosion, and Drain build-up rate by 20% |
| Lesser Ressurecter LEM | LEMs · Combat | Found in the world | Reduces Revive time by 20% |
| Lesser Runner LEM | LEMs · Movement | Found in the world | Increases Stamina Regen by 20% |
| Lesser Scalper LEM | LEMs · Combat | Found in the world | Increases item drop chance by 15% |
| Lesser Shieldfixer LEM | LEMs · Combat | Found in the world | Reduces Shield Recharge delay by 25% |
| Lesser Shieldgiver LEM | LEMs · Combat | Found in the world | Increases Max Shield by 20 |
