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StarRupture Nanosyringe Blueprint Location

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Written by Soloboom
Posted on March 27, 2026
Categories:
StarRupture

The Nanosyringe Blueprint is located in the right-hand building at the top of the MRO “Sky Star” outpost, situated just North of your starting ship. Getting your hands on better medical tech is always a good idea in this game, and this particular run is fairly short and straightforward if you manage your timing well.

Where to Find the Nanosyringe Blueprint in StarRupture

To find the Nanosyringe Blueprint, you need to make a quick trip to the MRO “Sky Star” location and climb to the upper structures. It is a very small outpost with minimal loot, but the schematic itself makes the trip entirely worth it.

StarRupture Nano Syringe Blueprint Location

1. Heading North to MRO Sky Star

Because base locations vary wildly from player to player, we will use the starting ship, or Orbital Lander, as our universal landmark. From the ship, set your heading directly North. As you will see, it is not too far of a walk to reach the MRO “Sky Star” facility, making this one of the easier navigation routes.

2. Preparing for the Weather

Even though it is a short trip, I always advise building a small habitat once you arrive. The weather on this planet is unforgiving, and having a safe place to hide in case a Rupture hits while you are busy looting is just common sense. It saves you the headache of running all the way back if things go wrong.

3. Timing Your Approach and Combat

If you want to avoid a firefight, the absolute best time to do this run is immediately after a Rupture. The heat clears out the alien spawns, leaving the area completely empty. If you decide to go during a normal weather cycle, expect a few enemies guarding the path. Head towards the elevated structures above and kill any alien that spawns as you make your climb.

4. Securing the Blueprint and Audio Log

Once you reach the top of the facility, you will notice there are only two buildings. You can either jump over the gap between the structures or safely walk around it. Head into the building on the right-hand side.

Gap to jump

There is not much general loot here, but grab what little scrap there is. Most importantly, you will find the Nanosyringe Blueprint inside. While you are here, you can also listen to a rather depressing audio log about a family dealing with a constantly creaking base, which I thought was a nice, grounded touch to the world-building.

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